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Pro-resolving lipid mediator lipoxin A(4) attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome
The chronic neuro-inflammatory character of multiple sclerosis (MS) suggests that the natural process to resolve inflammation is impaired. This protective process is orchestrated by specialized pro-resolving lipid mediators (SPMs), but to date, the role of SPMs in MS remains largely unknown. Here, w...
Autores principales: | Troletti, Claudio Derada, Enzmann, Gaby, Chiurchiù, Valerio, Kamermans, Alwin, Tietz, Silvia Martina, Norris, Paul C., Jahromi, Neda Haghayegh, Leuti, Alessandro, van der Pol, Susanne M.A., Schouten, Marijn, Serhan, Charles N., de Vries, Helga E., Engelhardt, Britta, Kooij, Gijs |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491454/ https://www.ncbi.nlm.nih.gov/pubmed/34077725 http://dx.doi.org/10.1016/j.celrep.2021.109201 |
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