Crystal structure of 2-{[5-amino-1-(phenyl­sulfon­yl)-1H-pyrazol-3-yl]­oxy}-1-(4-methyl­phen­yl)ethan-1-one

In the title compound, C(18)H(17)N(3)O(4)S, the pyrazole ring is planar, with the sulfur atom lying 0.558 (1) Å out of the ring plane. The NH(2) group is involved in an intra­molecular hydrogen bond to a sulfonyl oxygen atom; its other hydrogen atom forms an asymmetric three-centre hydrogen bond to...

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Autores principales: Metwally, Nadia H., Elgemeie, Galal H., Jones, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491526/
https://www.ncbi.nlm.nih.gov/pubmed/34667637
http://dx.doi.org/10.1107/S2056989021010008
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author Metwally, Nadia H.
Elgemeie, Galal H.
Jones, Peter G.
author_facet Metwally, Nadia H.
Elgemeie, Galal H.
Jones, Peter G.
author_sort Metwally, Nadia H.
collection PubMed
description In the title compound, C(18)H(17)N(3)O(4)S, the pyrazole ring is planar, with the sulfur atom lying 0.558 (1) Å out of the ring plane. The NH(2) group is involved in an intra­molecular hydrogen bond to a sulfonyl oxygen atom; its other hydrogen atom forms an asymmetric three-centre hydrogen bond to the two oxygen atoms of the —O—CH(2)—C=O— grouping, via the 2(1) screw axis, forming a ribbon structure parallel to the b axis. Translationally adjacent, coplanar ribbons form a layer parallel to (10[Image: see text]).
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spelling pubmed-84915262021-10-18 Crystal structure of 2-{[5-amino-1-(phenyl­sulfon­yl)-1H-pyrazol-3-yl]­oxy}-1-(4-methyl­phen­yl)ethan-1-one Metwally, Nadia H. Elgemeie, Galal H. Jones, Peter G. Acta Crystallogr E Crystallogr Commun Research Communications In the title compound, C(18)H(17)N(3)O(4)S, the pyrazole ring is planar, with the sulfur atom lying 0.558 (1) Å out of the ring plane. The NH(2) group is involved in an intra­molecular hydrogen bond to a sulfonyl oxygen atom; its other hydrogen atom forms an asymmetric three-centre hydrogen bond to the two oxygen atoms of the —O—CH(2)—C=O— grouping, via the 2(1) screw axis, forming a ribbon structure parallel to the b axis. Translationally adjacent, coplanar ribbons form a layer parallel to (10[Image: see text]). International Union of Crystallography 2021-09-30 /pmc/articles/PMC8491526/ /pubmed/34667637 http://dx.doi.org/10.1107/S2056989021010008 Text en © Metwally et al. 2021 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Communications
Metwally, Nadia H.
Elgemeie, Galal H.
Jones, Peter G.
Crystal structure of 2-{[5-amino-1-(phenyl­sulfon­yl)-1H-pyrazol-3-yl]­oxy}-1-(4-methyl­phen­yl)ethan-1-one
title Crystal structure of 2-{[5-amino-1-(phenyl­sulfon­yl)-1H-pyrazol-3-yl]­oxy}-1-(4-methyl­phen­yl)ethan-1-one
title_full Crystal structure of 2-{[5-amino-1-(phenyl­sulfon­yl)-1H-pyrazol-3-yl]­oxy}-1-(4-methyl­phen­yl)ethan-1-one
title_fullStr Crystal structure of 2-{[5-amino-1-(phenyl­sulfon­yl)-1H-pyrazol-3-yl]­oxy}-1-(4-methyl­phen­yl)ethan-1-one
title_full_unstemmed Crystal structure of 2-{[5-amino-1-(phenyl­sulfon­yl)-1H-pyrazol-3-yl]­oxy}-1-(4-methyl­phen­yl)ethan-1-one
title_short Crystal structure of 2-{[5-amino-1-(phenyl­sulfon­yl)-1H-pyrazol-3-yl]­oxy}-1-(4-methyl­phen­yl)ethan-1-one
title_sort crystal structure of 2-{[5-amino-1-(phenyl­sulfon­yl)-1h-pyrazol-3-yl]­oxy}-1-(4-methyl­phen­yl)ethan-1-one
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491526/
https://www.ncbi.nlm.nih.gov/pubmed/34667637
http://dx.doi.org/10.1107/S2056989021010008
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