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Novel Hemizygous Mutations of TEX11 Cause Meiotic Arrest and Non-obstructive Azoospermia in Chinese Han Population

Testis-expressed gene 11 (TEX11) mutation has been associated with non-obstructive azoospermia (NOA) and meiotic arrest. An analogous mutation of TEX11 in the mouse impairs meiosis and can be rescued by in vitro expansion of SSCs and gene therapy. However, a lack of genetic screening of a large coho...

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Detalles Bibliográficos
Autores principales:	Ji, Zhiyong, Yao, Chencheng, Yang, Chao, Huang, Chuan, Zhao, Liangyu, Han, Xia, Zhu, Zijue, Zhi, Erlei, Liu, Nachuan, Zhou, Zhi, Li, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491544/ https://www.ncbi.nlm.nih.gov/pubmed/34621296 http://dx.doi.org/10.3389/fgene.2021.741355

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