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Pristimerin inhibits neuronal inflammation and protects cognitive function in mice with sepsis-induced brain injuries by regulating PI3K/Akt signalling
CONTEXT: Sepsis is a systemic inflammatory disease; pristimerin exhibits strong antibacterial, anti-inflammatory and antioxidant properties. OBJECTIVES: We explored whether pristimerin protected against cognitive dysfunction and neuroinflammation in C57BL/6 J mice with sepsis-induced brain injuries....
Autori principali: | , , |
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Natura: | Online Articolo testo |
Lingua: | English |
Pubblicazione: |
Taylor & Francis
2021
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Accesso online: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491740/ https://www.ncbi.nlm.nih.gov/pubmed/34590530 http://dx.doi.org/10.1080/13880209.2021.1981399 |