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Pristimerin inhibits neuronal inflammation and protects cognitive function in mice with sepsis-induced brain injuries by regulating PI3K/Akt signalling

CONTEXT: Sepsis is a systemic inflammatory disease; pristimerin exhibits strong antibacterial, anti-inflammatory and antioxidant properties. OBJECTIVES: We explored whether pristimerin protected against cognitive dysfunction and neuroinflammation in C57BL/6 J mice with sepsis-induced brain injuries....

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Bibliografske podrobnosti
Autores principales: Xue, Weimin, Li, Yaqiang, Zhang, Mei
Format: Online Artículo Texto
Jezik:English
Izdano: Taylor & Francis 2021
Teme:
Online dostop:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491740/
https://www.ncbi.nlm.nih.gov/pubmed/34590530
http://dx.doi.org/10.1080/13880209.2021.1981399