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Drug-induced resistance evolution necessitates less aggressive treatment

Increasing body of experimental evidence suggests that anticancer and antimicrobial therapies may themselves promote the acquisition of drug resistance by increasing mutability. The successful control of evolving populations requires that such biological costs of control are identified, quantified a...

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Detalles Bibliográficos
Autores principales: Kuosmanen, Teemu, Cairns, Johannes, Noble, Robert, Beerenwinkel, Niko, Mononen, Tommi, Mustonen, Ville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491903/
https://www.ncbi.nlm.nih.gov/pubmed/34555024
http://dx.doi.org/10.1371/journal.pcbi.1009418