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Identifying causal variants by fine mapping across multiple studies

Increasingly large Genome-Wide Association Studies (GWAS) have yielded numerous variants associated with many complex traits, motivating the development of “fine mapping” methods to identify which of the associated variants are causal. Additionally, GWAS of the same trait for different populations a...

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Detalles Bibliográficos
Autores principales: LaPierre, Nathan, Taraszka, Kodi, Huang, Helen, He, Rosemary, Hormozdiari, Farhad, Eskin, Eleazar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491908/
https://www.ncbi.nlm.nih.gov/pubmed/34543273
http://dx.doi.org/10.1371/journal.pgen.1009733