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The impact of disease-related knowledge on perceptions of stigma among patients with Hepatitis C Virus (HCV) infection

Most patients with hepatitis C virus (HCV) infection perceive some degree of disease-related stigma. Misunderstandings about diseases may contribute to disease-related stigma. The objective of this study was to evaluate patient-level knowledge about HCV infection transmission and natural history and...

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Autores principales: Saine, M. Elle, Szymczak, Julia E., Moore, Tyler M., Bamford, Laura P., Barg, Frances K., Forde, Kimberly A., Schnittker, Jason, Holmes, John H., Mitra, Nandita, Lo Re, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491913/
https://www.ncbi.nlm.nih.gov/pubmed/34610030
http://dx.doi.org/10.1371/journal.pone.0258143
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author Saine, M. Elle
Szymczak, Julia E.
Moore, Tyler M.
Bamford, Laura P.
Barg, Frances K.
Forde, Kimberly A.
Schnittker, Jason
Holmes, John H.
Mitra, Nandita
Lo Re, Vincent
author_facet Saine, M. Elle
Szymczak, Julia E.
Moore, Tyler M.
Bamford, Laura P.
Barg, Frances K.
Forde, Kimberly A.
Schnittker, Jason
Holmes, John H.
Mitra, Nandita
Lo Re, Vincent
author_sort Saine, M. Elle
collection PubMed
description Most patients with hepatitis C virus (HCV) infection perceive some degree of disease-related stigma. Misunderstandings about diseases may contribute to disease-related stigma. The objective of this study was to evaluate patient-level knowledge about HCV infection transmission and natural history and its association with HCV-related stigma among HCV-infected patients. We conducted a cross-sectional survey study among 265 patients with HCV in Philadelphia using the HCV Stigma Scale and the National Health and Nutrition Examination Survey (NHANES) Hepatitis C Follow-up Survey (2001–2008). The association between HCV knowledge and HCV-related stigma was evaluated via linear regression. Overall knowledge about HCV transmission and natural history was high, with >80% of participants answering ≥9 of 11 items correctly (median number of correct responses, 9 [82%]), HCV-related knowledge was similar between HIV/HCV-coinfected and HCV-monoinfected participants (p = 0.30). A higher level of HCV-related knowledge was associated with greater perceived HCV-related stigma (β, 2.34 ([95% CI, 0.51–4.17]; p = 0.013). Results were similar after adjusting for age, race, ethnicity, HIV status, education level, stage of HCV management, time since diagnosis, and history of injection drug use. In this study, increased HCV-related knowledge was associated with greater perceptions of HCV stigma. Clinicians may consider allotting time to address common misconceptions about HCV when educating patients about HCV infection, which may counterbalance the stigmatizing impact of greater HCV-related knowledge.
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spelling pubmed-84919132021-10-06 The impact of disease-related knowledge on perceptions of stigma among patients with Hepatitis C Virus (HCV) infection Saine, M. Elle Szymczak, Julia E. Moore, Tyler M. Bamford, Laura P. Barg, Frances K. Forde, Kimberly A. Schnittker, Jason Holmes, John H. Mitra, Nandita Lo Re, Vincent PLoS One Research Article Most patients with hepatitis C virus (HCV) infection perceive some degree of disease-related stigma. Misunderstandings about diseases may contribute to disease-related stigma. The objective of this study was to evaluate patient-level knowledge about HCV infection transmission and natural history and its association with HCV-related stigma among HCV-infected patients. We conducted a cross-sectional survey study among 265 patients with HCV in Philadelphia using the HCV Stigma Scale and the National Health and Nutrition Examination Survey (NHANES) Hepatitis C Follow-up Survey (2001–2008). The association between HCV knowledge and HCV-related stigma was evaluated via linear regression. Overall knowledge about HCV transmission and natural history was high, with >80% of participants answering ≥9 of 11 items correctly (median number of correct responses, 9 [82%]), HCV-related knowledge was similar between HIV/HCV-coinfected and HCV-monoinfected participants (p = 0.30). A higher level of HCV-related knowledge was associated with greater perceived HCV-related stigma (β, 2.34 ([95% CI, 0.51–4.17]; p = 0.013). Results were similar after adjusting for age, race, ethnicity, HIV status, education level, stage of HCV management, time since diagnosis, and history of injection drug use. In this study, increased HCV-related knowledge was associated with greater perceptions of HCV stigma. Clinicians may consider allotting time to address common misconceptions about HCV when educating patients about HCV infection, which may counterbalance the stigmatizing impact of greater HCV-related knowledge. Public Library of Science 2021-10-05 /pmc/articles/PMC8491913/ /pubmed/34610030 http://dx.doi.org/10.1371/journal.pone.0258143 Text en © 2021 Saine et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Saine, M. Elle
Szymczak, Julia E.
Moore, Tyler M.
Bamford, Laura P.
Barg, Frances K.
Forde, Kimberly A.
Schnittker, Jason
Holmes, John H.
Mitra, Nandita
Lo Re, Vincent
The impact of disease-related knowledge on perceptions of stigma among patients with Hepatitis C Virus (HCV) infection
title The impact of disease-related knowledge on perceptions of stigma among patients with Hepatitis C Virus (HCV) infection
title_full The impact of disease-related knowledge on perceptions of stigma among patients with Hepatitis C Virus (HCV) infection
title_fullStr The impact of disease-related knowledge on perceptions of stigma among patients with Hepatitis C Virus (HCV) infection
title_full_unstemmed The impact of disease-related knowledge on perceptions of stigma among patients with Hepatitis C Virus (HCV) infection
title_short The impact of disease-related knowledge on perceptions of stigma among patients with Hepatitis C Virus (HCV) infection
title_sort impact of disease-related knowledge on perceptions of stigma among patients with hepatitis c virus (hcv) infection
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491913/
https://www.ncbi.nlm.nih.gov/pubmed/34610030
http://dx.doi.org/10.1371/journal.pone.0258143
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