Characterization of changes in the hemagglutinin that accompanied the emergence of H3N2/1968 pandemic influenza viruses

The hemagglutinin (HA) of A/H3N2 pandemic influenza viruses (IAVs) of 1968 differed from its inferred avian precursor by eight amino acid substitutions. To determine their phenotypic effects, we studied recombinant variants of A/Hong Kong/1/1968 virus containing either human-type or avian-type amino...

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Detalles Bibliográficos
Autores principales: West, Johanna, Röder, Juliane, Matrosovich, Tatyana, Beicht, Jana, Baumann, Jan, Mounogou Kouassi, Nancy, Doedt, Jennifer, Bovin, Nicolai, Zamperin, Gianpiero, Gastaldelli, Michele, Salviato, Annalisa, Bonfante, Francesco, Kosakovsky Pond, Sergei, Herfst, Sander, Fouchier, Ron, Wilhelm, Jochen, Klenk, Hans-Dieter, Matrosovich, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491938/
https://www.ncbi.nlm.nih.gov/pubmed/34555124
http://dx.doi.org/10.1371/journal.ppat.1009566

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