Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte glycoprotein antibodies following SARS-CoV-2 infection

We report the case of a patient with symptoms of myelopathy following acute SARS-CoV-2 infection. MRI documented a longitudinally extensive transverse myelitis and further investigation was unremarkable with the exception of positivity for MOG-IgG in serum. This report extends the spectrum of post-C...

Descripción completa

Detalles Bibliográficos
Autores principales: Dias da Costa, Mariana, Leal Rato, Miguel, Cruz, Diana, Valadas, Anabela, Antunes, Ana Patrícia, Albuquerque, Luísa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492014/
https://www.ncbi.nlm.nih.gov/pubmed/34628134
http://dx.doi.org/10.1016/j.jneuroim.2021.577739
_version_ 1784578846911102976
author Dias da Costa, Mariana
Leal Rato, Miguel
Cruz, Diana
Valadas, Anabela
Antunes, Ana Patrícia
Albuquerque, Luísa
author_facet Dias da Costa, Mariana
Leal Rato, Miguel
Cruz, Diana
Valadas, Anabela
Antunes, Ana Patrícia
Albuquerque, Luísa
author_sort Dias da Costa, Mariana
collection PubMed
description We report the case of a patient with symptoms of myelopathy following acute SARS-CoV-2 infection. MRI documented a longitudinally extensive transverse myelitis and further investigation was unremarkable with the exception of positivity for MOG-IgG in serum. This report extends the spectrum of post-COVID-19 neurological syndromes, and documents a very significant improvement to long-term oral corticosteroid therapy in this setting. Further prospective studies are needed to establish the risk of recurrence in this subset of patients.
format Online
Article
Text
id pubmed-8492014
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-84920142021-10-06 Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte glycoprotein antibodies following SARS-CoV-2 infection Dias da Costa, Mariana Leal Rato, Miguel Cruz, Diana Valadas, Anabela Antunes, Ana Patrícia Albuquerque, Luísa J Neuroimmunol Short Communication We report the case of a patient with symptoms of myelopathy following acute SARS-CoV-2 infection. MRI documented a longitudinally extensive transverse myelitis and further investigation was unremarkable with the exception of positivity for MOG-IgG in serum. This report extends the spectrum of post-COVID-19 neurological syndromes, and documents a very significant improvement to long-term oral corticosteroid therapy in this setting. Further prospective studies are needed to establish the risk of recurrence in this subset of patients. Elsevier B.V. 2021-12-15 2021-10-05 /pmc/articles/PMC8492014/ /pubmed/34628134 http://dx.doi.org/10.1016/j.jneuroim.2021.577739 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Dias da Costa, Mariana
Leal Rato, Miguel
Cruz, Diana
Valadas, Anabela
Antunes, Ana Patrícia
Albuquerque, Luísa
Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte glycoprotein antibodies following SARS-CoV-2 infection
title Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte glycoprotein antibodies following SARS-CoV-2 infection
title_full Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte glycoprotein antibodies following SARS-CoV-2 infection
title_fullStr Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte glycoprotein antibodies following SARS-CoV-2 infection
title_full_unstemmed Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte glycoprotein antibodies following SARS-CoV-2 infection
title_short Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte glycoprotein antibodies following SARS-CoV-2 infection
title_sort longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte glycoprotein antibodies following sars-cov-2 infection
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492014/
https://www.ncbi.nlm.nih.gov/pubmed/34628134
http://dx.doi.org/10.1016/j.jneuroim.2021.577739
work_keys_str_mv AT diasdacostamariana longitudinallyextensivetransversemyelitiswithantimyelinoligodendrocyteglycoproteinantibodiesfollowingsarscov2infection
AT lealratomiguel longitudinallyextensivetransversemyelitiswithantimyelinoligodendrocyteglycoproteinantibodiesfollowingsarscov2infection
AT cruzdiana longitudinallyextensivetransversemyelitiswithantimyelinoligodendrocyteglycoproteinantibodiesfollowingsarscov2infection
AT valadasanabela longitudinallyextensivetransversemyelitiswithantimyelinoligodendrocyteglycoproteinantibodiesfollowingsarscov2infection
AT antunesanapatricia longitudinallyextensivetransversemyelitiswithantimyelinoligodendrocyteglycoproteinantibodiesfollowingsarscov2infection
AT albuquerqueluisa longitudinallyextensivetransversemyelitiswithantimyelinoligodendrocyteglycoproteinantibodiesfollowingsarscov2infection

Ejemplares similares