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Wogonin Alleviates Cisplatin-induced Cardiotoxicity in Mice Via Inhibiting Gasdermin D-mediated Pyroptosis

Cardiotoxicity has been well documented as a side effect of cisplatin (CDDP) treatment. The inflammatory response plays a crucial role in the pathological process of CDDP-induced cardiotoxicity. Wogonin is a natural flavonoid compound that possesses cardioprotective and anti-inflammatory qualities....

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Detalles Bibliográficos
Autores principales: Xu, Jiajun, Zhang, Bin, Chu, Zhenliang, Jiang, Fenfen, Han, Jibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492184/
https://www.ncbi.nlm.nih.gov/pubmed/34651602
http://dx.doi.org/10.1097/FJC.0000000000001085