Increased plasma XOR activity induced by NAFLD/NASH and its possible involvement in vascular neointimal proliferation

Xanthine oxidoreductase (XOR) is an enzyme that catalyzes hypoxanthine to xanthine and xanthine to uric acid, respectively. However, the underlying mechanisms of increased plasma XOR and its pathological roles in systemic diseases, such as atherosclerosis, are not fully understood. In this study, we...

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Detalles Bibliográficos
Autores principales: Kawachi, Yusuke, Fujishima, Yuya, Nishizawa, Hitoshi, Nakamura, Takashi, Akari, Seigo, Murase, Takayo, Saito, Takuro, Miyazaki, Yasuhiro, Nagao, Hirofumi, Fukuda, Shiro, Kita, Shunbun, Katakami, Naoto, Doki, Yuichiro, Maeda, Norikazu, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492303/
https://www.ncbi.nlm.nih.gov/pubmed/34494551
http://dx.doi.org/10.1172/jci.insight.144762

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