COVID-19 generates hyaluronan fragments that directly induce endothelial barrier dysfunction

Vascular injury has emerged as a complication contributing to morbidity in coronavirus disease 2019 (COVID-19). The glycosaminoglycan hyaluronan (HA) is a major component of the glycocalyx, a protective layer of glycoconjugates that lines the vascular lumen and regulates key endothelial cell functio...

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Detalles Bibliográficos
Autores principales: Queisser, Kimberly A., Mellema, Rebecca A., Middleton, Elizabeth A., Portier, Irina, Manne, Bhanu Kanth, Denorme, Frederik, Beswick, Ellen J., Rondina, Matthew T., Campbell, Robert A., Petrey, Aaron C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492325/
https://www.ncbi.nlm.nih.gov/pubmed/34314391
http://dx.doi.org/10.1172/jci.insight.147472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492325/
https://www.ncbi.nlm.nih.gov/pubmed/34314391
http://dx.doi.org/10.1172/jci.insight.147472

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