Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1

Mitochondrial biogenesis and function are controlled by anterograde regulatory pathways involving more than 1000 nuclear-encoded proteins. Transcriptional networks controlling the nuclear-encoded mitochondrial genes remain to be fully elucidated. Here, we show that histone demethylase LSD1 KO from a...

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Detalles Bibliográficos
Autores principales: Cao, Yang, Tang, Lingyi, Du, Kang, Paraiso, Kitt, Sun, Qiushi, Liu, Zhengxia, Ye, Xiaolong, Fang, Yuan, Yuan, Fang, Chen, Hank, Chen, Yumay, Wang, Xiaorong, Yu, Clinton, Blitz, Ira L., Wang, Ping H., Huang, Lan, Cheng, Haibo, Lu, Xiang, Cho, Ken W.Y., Seldin, Marcus, Fang, Zhuyuan, Yang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492328/
https://www.ncbi.nlm.nih.gov/pubmed/34314389
http://dx.doi.org/10.1172/jci.insight.147692

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