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Safety and PCR monitoring in 161 semi-immune Kenyan adults following controlled human malaria infection

BACKGROUND: Naturally acquired immunity to malaria is incompletely understood. We used controlled human malaria infection (CHMI) to study the impact of past exposure on malaria in Kenyan adults in relation to infection with a non-Kenyan parasite strain. METHODS: We administered 3.2 × 10(3) aseptic,...

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Detalles Bibliográficos
Autores principales: Kapulu, Melissa C., Njuguna, Patricia, Hamaluba, Mainga, Kimani, Domtila, Ngoi, Joyce M., Musembi, Janet, Ngoto, Omar, Otieno, Edward, Billingsley, Peter F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492329/
https://www.ncbi.nlm.nih.gov/pubmed/34264864
http://dx.doi.org/10.1172/jci.insight.146443