IFN-γ is essential for alveolar macrophage–driven pulmonary inflammation in macrophage activation syndrome

Macrophage activation syndrome (MAS) is a life-threatening cytokine storm complicating systemic juvenile idiopathic arthritis (SJIA) driven by IFN-γ. SJIA and MAS are also associated with an unexplained emerging inflammatory lung disease (SJIA-LD), with our recent work supporting pulmonary activatio...

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Detalles Bibliográficos
Autores principales: Gao, Denny K., Salomonis, Nathan, Henderlight, Maggie, Woods, Christopher, Thakkar, Kairavee, Grom, Alexei A., Thornton, Sherry, Jordan, Michael B., Wikenheiser-Brokamp, Kathryn A., Schulert, Grant S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492332/
https://www.ncbi.nlm.nih.gov/pubmed/34314387
http://dx.doi.org/10.1172/jci.insight.147593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492332/
https://www.ncbi.nlm.nih.gov/pubmed/34314387
http://dx.doi.org/10.1172/jci.insight.147593

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