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PERK in POMC neurons connects celastrol with metabolism

ER stress and activation of the unfolded protein response in the periphery as well as the central nervous system have been linked to various metabolic abnormalities. Chemically lowering protein kinase R–like ER kinase (PERK) activity within the hypothalamus leads to decreased food intake and body we...

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Detalles Bibliográficos
Autores principales:	He, Zhenyan, Lieu, Linh, Dong, Yanbin, Afrin, Sadia, Chau, Dominic, Kabahizi, Anita, Wallace, Briana, Cao, Jianhong, Hwang, Eun-Sang, Yao, Ting, Huang, Yiru, Okolo, Jennifer, Cheng, Bo, Gao, Yong, Hu, Ling, Williams, Kevin W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492333/ https://www.ncbi.nlm.nih.gov/pubmed/34549728 http://dx.doi.org/10.1172/jci.insight.145306

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