Cardiomyocyte microRNA-150 confers cardiac protection and directly represses proapoptotic small proline–rich protein 1A

MicroRNA-150 (miR-150) is downregulated in patients with multiple cardiovascular diseases and in diverse mouse models of heart failure (HF). miR-150 is significantly associated with HF severity and outcome in humans. We previously reported that miR-150 is activated by β-blocker carvedilol (Carv) and...

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Detalles Bibliográficos
Autores principales: Aonuma, Tatsuya, Moukette, Bruno, Kawaguchi, Satoshi, Barupala, Nipuni P., Sepúlveda, Marisa N., Corr, Christopher, Tang, Yaoliang, Liangpunsakul, Suthat, Payne, R. Mark, Willis, Monte S., Kim, Il-man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492334/
https://www.ncbi.nlm.nih.gov/pubmed/34403363
http://dx.doi.org/10.1172/jci.insight.150405

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