DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis

Pancreatic ductal adenocarcinoma (PDAC) tumors are characterized by a desmoplastic reaction resulting in dense deposition of collagen that is known to promote cancer progression. A central mediator of protumorigenic collagen signaling is the receptor tyrosine kinase discoid domain receptor 1 (DDR1)....

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Detalles Bibliográficos
Autores principales: Deng, Jenying, Kang, Yaan, Cheng, Chien-Chia, Li, Xinqun, Dai, Bingbing, Katz, Matthew H., Men, Taoyan, Kim, Michael P., Koay, Eugene A., Huang, Huocong, Brekken, Rolf A., Fleming, Jason B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492346/
https://www.ncbi.nlm.nih.gov/pubmed/34237033
http://dx.doi.org/10.1172/jci.insight.146133

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