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Fatty acid mobilization from adipose tissue is mediated by CD36 posttranslational modifications and intracellular trafficking
The mechanism controlling long-chain fatty acid (LCFA) mobilization from adipose tissue is not well understood. Here, we investigated how the LCFA transporter CD36 regulates this process. By using tissue-specific KO mouse models, we showed that CD36 in adipocytes and endothelial cells mediated both...
Autores principales: | Daquinag, Alexes C., Gao, Zhanguo, Fussell, Cale, Immaraj, Linnet, Pasqualini, Renata, Arap, Wadih, Akimzhanov, Askar M., Febbraio, Maria, Kolonin, Mikhail G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492349/ https://www.ncbi.nlm.nih.gov/pubmed/34314388 http://dx.doi.org/10.1172/jci.insight.147057 |
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