MG53 suppresses NF-κB activation to mitigate age-related heart failure

Aging is associated with chronic oxidative stress and inflammation that affect tissue repair and regeneration capacity. MG53 is a TRIM family protein that facilitates repair of cell membrane injury in a redox-dependent manner. Here, we demonstrate that the expression of MG53 was reduced in failing h...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoliang, Li, Xiuchun, Ong, Hannah, Tan, Tao, Park, Ki Ho, Bian, Zehua, Zou, Xunchang, Haggard, Erin, Janssen, Paul M., Merritt, Robert E., Pawlik, Timothy M., Whitson, Bryan A., Mokadam, Nahush A., Cao, Lei, Zhu, Hua, Cai, Chuanxi, Ma, Jianjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492351/
https://www.ncbi.nlm.nih.gov/pubmed/34292883
http://dx.doi.org/10.1172/jci.insight.148375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492351/
https://www.ncbi.nlm.nih.gov/pubmed/34292883
http://dx.doi.org/10.1172/jci.insight.148375

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