Seroprevalence of SARS-CoV-2 immunoglobulins in pregnant women and neonatal cord blood from a highly impacted region

There is inadequate screening for SARS-COV-2 during pregnancy. We aimed to determine the impact of maternal and neonatal cord blood SARS-COV-2 antibodies and placental transfer ratios in a region with a low screening plan. We performed a blind study in one of the SARS-CoV-2 epicenters in South Ameri...

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Detalles Bibliográficos
Autores principales: Zambrano, Hector, Anchundia, Ketty, Aviles, Dalila, Andaluz, Ruffo, Calderon, Nathaly, Torres, Estefanie, Gonzalez-Granda, Nicolas, Maxwell, Anthony, Chen, Kang, Gonik, Bernard, Mor, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492380/
https://www.ncbi.nlm.nih.gov/pubmed/34626893
http://dx.doi.org/10.1016/j.placenta.2021.10.001
Descripción
Sumario:There is inadequate screening for SARS-COV-2 during pregnancy. We aimed to determine the impact of maternal and neonatal cord blood SARS-COV-2 antibodies and placental transfer ratios in a region with a low screening plan. We performed a blind study in one of the SARS-CoV-2 epicenters in South America. 32% of pregnant women were serological positive. Importantly, there is an efficient passive immunization of the fetus to SARS-CoV-2. We report high incidence of SARS-CoV-2 infection during pregnancy, which is higher than officially reported. Therefore the need of active immunization to enhance maternal protection and fetal passive immunization.

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