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The possibility of low isomerization of β-lapachone in the human body

β-Lapachone has been reported to have anticancer and various other therapeutic effects, but is limited in clinical applications by its low bioavailability. pH-Dependent isomerization can be suggested as one plausible factor influencing its low bioavailability. Since it is known that β-lapachone is c...

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Detalles Bibliográficos
Autores principales: Lee, Kyung Min, Gwon, Mi-Ri, Lee, Hae Won, Seong, Sook Jin, Yoon, Young-Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492396/
https://www.ncbi.nlm.nih.gov/pubmed/34621708
http://dx.doi.org/10.12793/tcp.2021.29.e16