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District Differences in the Measured Values of Arterial Stiffness in Japan
Background: In Japan, district differences in the prevalence of cardiovascular disease (CVD) are well-known. This study examined district differences in Japan in measured values of arterial stiffness, an independent risk factor for CVD. Methods and Results: Local residents participating in health ch...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Circulation Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492401/ https://www.ncbi.nlm.nih.gov/pubmed/34703940 http://dx.doi.org/10.1253/circrep.CR-21-0064 |
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author | Miyai, Nobuyuki Uchiba, Kiyoshi Tomiyama, Hirofumi Matsumoto, Chisa Kinoshita, Azuna Vlachoupolos, Charalambos Nilsson, Peter M. Arita, Mikio |
author_facet | Miyai, Nobuyuki Uchiba, Kiyoshi Tomiyama, Hirofumi Matsumoto, Chisa Kinoshita, Azuna Vlachoupolos, Charalambos Nilsson, Peter M. Arita, Mikio |
author_sort | Miyai, Nobuyuki |
collection | PubMed |
description | Background: In Japan, district differences in the prevalence of cardiovascular disease (CVD) are well-known. This study examined district differences in Japan in measured values of arterial stiffness, an independent risk factor for CVD. Methods and Results: Local residents participating in health checkups conducted in the Wakayama (n=461) and Nagano (n=186) prefectures in 2018 were recruited to the study. Brachial-ankle pulse wave velocity (baPWV) was evaluated as an index of arterial stiffness. After multivariate adjustment, baPWV was significantly higher in the Wakayama than Nagano district in subjects aged ≥70 years (mean [±SE] 1,912±25 vs. 1,763±30 cm/s; P<0.01), but not in subjects aged <70 years. Multivariate linear regression analysis demonstrated that the Wakayama/Nagano district difference was significantly (P<0.01) associated with baPWV. Conclusions: District differences were observed in the measured values of arterial stiffness in Wakayama and Nagano. The Wakayama and Nagano prefectures are representative areas with a relatively high and relatively low prevalence of CVD, respectively, in Japan. Therefore, based on the results of the present study, we propose to conduct a study to examine whether district differences in arterial stiffness underlie district differences in the prevalence of CVD. |
format | Online Article Text |
id | pubmed-8492401 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Japanese Circulation Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-84924012021-10-25 District Differences in the Measured Values of Arterial Stiffness in Japan Miyai, Nobuyuki Uchiba, Kiyoshi Tomiyama, Hirofumi Matsumoto, Chisa Kinoshita, Azuna Vlachoupolos, Charalambos Nilsson, Peter M. Arita, Mikio Circ Rep Brief Report Background: In Japan, district differences in the prevalence of cardiovascular disease (CVD) are well-known. This study examined district differences in Japan in measured values of arterial stiffness, an independent risk factor for CVD. Methods and Results: Local residents participating in health checkups conducted in the Wakayama (n=461) and Nagano (n=186) prefectures in 2018 were recruited to the study. Brachial-ankle pulse wave velocity (baPWV) was evaluated as an index of arterial stiffness. After multivariate adjustment, baPWV was significantly higher in the Wakayama than Nagano district in subjects aged ≥70 years (mean [±SE] 1,912±25 vs. 1,763±30 cm/s; P<0.01), but not in subjects aged <70 years. Multivariate linear regression analysis demonstrated that the Wakayama/Nagano district difference was significantly (P<0.01) associated with baPWV. Conclusions: District differences were observed in the measured values of arterial stiffness in Wakayama and Nagano. The Wakayama and Nagano prefectures are representative areas with a relatively high and relatively low prevalence of CVD, respectively, in Japan. Therefore, based on the results of the present study, we propose to conduct a study to examine whether district differences in arterial stiffness underlie district differences in the prevalence of CVD. The Japanese Circulation Society 2021-09-11 /pmc/articles/PMC8492401/ /pubmed/34703940 http://dx.doi.org/10.1253/circrep.CR-21-0064 Text en Copyright © 2021, THE JAPANESE CIRCULATION SOCIETY https://creativecommons.org/licenses/by-nc-nd/4.0/This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license. |
spellingShingle | Brief Report Miyai, Nobuyuki Uchiba, Kiyoshi Tomiyama, Hirofumi Matsumoto, Chisa Kinoshita, Azuna Vlachoupolos, Charalambos Nilsson, Peter M. Arita, Mikio District Differences in the Measured Values of Arterial Stiffness in Japan |
title | District Differences in the Measured Values of Arterial Stiffness in Japan |
title_full | District Differences in the Measured Values of Arterial Stiffness in Japan |
title_fullStr | District Differences in the Measured Values of Arterial Stiffness in Japan |
title_full_unstemmed | District Differences in the Measured Values of Arterial Stiffness in Japan |
title_short | District Differences in the Measured Values of Arterial Stiffness in Japan |
title_sort | district differences in the measured values of arterial stiffness in japan |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492401/ https://www.ncbi.nlm.nih.gov/pubmed/34703940 http://dx.doi.org/10.1253/circrep.CR-21-0064 |
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