NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype

Atherosclerosis and its consequences cause considerable morbidity and mortality world-wide. We have previously shown that expression of the DNA glycosylase NEIL3 is regulated in human atherosclerotic plaques, and that NEIL3-deficiency enhances atherogenesis in Apoe(−/−) mice. Herein, we identified a...

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Detalles Bibliográficos
Autores principales: Karlsen, Tom Rune, Kong, Xiang Yi, Holm, Sverre, Quiles-Jiménez, Ana, Dahl, Tuva B., Yang, Kuan, Sagen, Ellen L., Skarpengland, Tonje, S. Øgaard, Jonas D., Holm, Kristian, Vestad, Beate, Olsen, Maria B., Aukrust, Pål, Bjørås, Magnar, Hov, Johannes R., Halvorsen, Bente, Gregersen, Ida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492623/
https://www.ncbi.nlm.nih.gov/pubmed/34611194
http://dx.doi.org/10.1038/s41598-021-98820-0

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