Astrocytic YAP prevents the demyelination through promoting expression of cholesterol synthesis genes in experimental autoimmune encephalomyelitis

Cholesterols are the main components of myelin, and are mainly synthesized in astrocytes and transported to oligodendrocytes and neurons in the adult brain. It has been reported that Hippo/yes-associated protein (YAP) pathways are involved in cholesterol synthesis in the liver, however, it remains u...

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Detalles Bibliográficos
Autores principales: Zhang, Jingjing, Xu, Xingxing, Liu, Huitao, Jin, Lingting, Shen, Xiya, Xie, Changnan, Xiang, Weiwei, Yang, Danlu, Feng, Wenjin, Wang, Jiaojiao, Wang, Mianxian, Dong, Tianyingying, Qiu, Haoyu, Wu, Lihao, Wang, Ying, Zhang, Xu, Huang, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492624/
https://www.ncbi.nlm.nih.gov/pubmed/34611127
http://dx.doi.org/10.1038/s41419-021-04203-8

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