Cargando…

Antigen presentation by lung epithelial cells directs CD4(+) T(RM) cell function and regulates barrier immunity

Barrier tissues are populated by functionally plastic CD4(+) resident memory T (T(RM)) cells. Whether the barrier epithelium regulates CD4(+) T(RM) cell locations, plasticity and activities remains unclear. Here we report that lung epithelial cells, including distinct surfactant protein C (SPC)(low)...

Descripción completa

Detalles Bibliográficos
Autores principales: Shenoy, Anukul T., Lyon De Ana, Carolina, Arafa, Emad I., Salwig, Isabelle, Barker, Kimberly A., Korkmaz, Filiz T., Ramanujan, Aditya, Etesami, Neelou S., Soucy, Alicia M., Martin, Ian M. C., Tilton, Brian R., Hinds, Anne, Goltry, Wesley N., Kathuria, Hasmeena, Braun, Thomas, Jones, Matthew R., Quinton, Lee J., Belkina, Anna C., Mizgerd, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492657/
https://www.ncbi.nlm.nih.gov/pubmed/34611166
http://dx.doi.org/10.1038/s41467-021-26045-w

Ejemplares similares