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Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family members mediate receptor- and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody responses are a central component of naturally acquired malaria immunity. PfEMP1-specific IgG likely protects by inhibi...
Autores principales: | Larsen, Mads Delbo, Lopez-Perez, Mary, Dickson, Emmanuel Kakra, Ampomah, Paulina, Tuikue Ndam, Nicaise, Nouta, Jan, Koeleman, Carolien A. M., Ederveen, Agnes L. Hipgrave, Mordmüller, Benjamin, Salanti, Ali, Nielsen, Morten Agertoug, Massougbodji, Achille, van der Schoot, C. Ellen, Ofori, Michael F., Wuhrer, Manfred, Hviid, Lars, Vidarsson, Gestur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492741/ https://www.ncbi.nlm.nih.gov/pubmed/34611164 http://dx.doi.org/10.1038/s41467-021-26118-w |
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