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Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family members mediate receptor- and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody responses are a central component of naturally acquired malaria immunity. PfEMP1-specific IgG likely protects by inhibi...

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Detalles Bibliográficos
Autores principales: Larsen, Mads Delbo, Lopez-Perez, Mary, Dickson, Emmanuel Kakra, Ampomah, Paulina, Tuikue Ndam, Nicaise, Nouta, Jan, Koeleman, Carolien A. M., Ederveen, Agnes L. Hipgrave, Mordmüller, Benjamin, Salanti, Ali, Nielsen, Morten Agertoug, Massougbodji, Achille, van der Schoot, C. Ellen, Ofori, Michael F., Wuhrer, Manfred, Hviid, Lars, Vidarsson, Gestur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492741/
https://www.ncbi.nlm.nih.gov/pubmed/34611164
http://dx.doi.org/10.1038/s41467-021-26118-w

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