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Single-cell RNA sequencing reveals cell heterogeneity and transcriptome profile of breast cancer lymph node metastasis

Molecular mechanisms underlying breast cancer lymph node metastasis remain unclear. Using single-cell sequencing, we investigated the transcriptome profile of 96,796 single cells from 15 paired samples of primary tumors and axillary lymph nodes. We identified nine cancer cell subclusters including C...

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Detalles Bibliográficos
Autores principales: Xu, Kun, Wang, Runtian, Xie, Hui, Hu, Longfei, Wang, Cong, Xu, Jiali, Zhu, Chengjun, Liu, Yiqiu, Gao, Fangyan, Li, Xintong, Wang, Cenzhu, Huang, Jinyi, Zhou, Wenbin, Zhou, Guohua, Shu, Yongqian, Guan, Xiaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492772/
https://www.ncbi.nlm.nih.gov/pubmed/34611125
http://dx.doi.org/10.1038/s41389-021-00355-6