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Replicating Cortical Signatures May Open the Possibility for “Transplanting” Brain States via Brain Entrainment

Brain states, which correlate with specific motor, cognitive, and emotional states, may be monitored with noninvasive techniques such as electroencephalography (EEG) and magnetoencephalography (MEG) that measure macroscopic cortical activity manifested as oscillatory network dynamics. These rhythmic...

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Autor principal: Poltorak, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492906/
https://www.ncbi.nlm.nih.gov/pubmed/34630058
http://dx.doi.org/10.3389/fnhum.2021.710003
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author Poltorak, Alexander
author_facet Poltorak, Alexander
author_sort Poltorak, Alexander
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description Brain states, which correlate with specific motor, cognitive, and emotional states, may be monitored with noninvasive techniques such as electroencephalography (EEG) and magnetoencephalography (MEG) that measure macroscopic cortical activity manifested as oscillatory network dynamics. These rhythmic cortical signatures provide insight into the neuronal activity used to identify pathological cortical function in numerous neurological and psychiatric conditions. Sensory and transcranial stimulation, entraining the brain with specific brain rhythms, can effectively induce desired brain states (such as state of sleep or state of attention) correlated with such cortical rhythms. Because brain states have distinct neural correlates, it may be possible to induce a desired brain state by replicating these neural correlates through stimulation. To do so, we propose recording brain waves from a “donor” in a particular brain state using EEG/MEG to extract cortical signatures of the brain state. These cortical signatures would then be inverted and used to entrain the brain of a “recipient” via sensory or transcranial stimulation. We propose that brain states may thus be transferred between people by acquiring an associated cortical signature from a donor, which, following processing, may be applied to a recipient through sensory or transcranial stimulation. This technique may provide a novel and effective neuromodulation approach to the noninvasive, non-pharmacological treatment of a variety of psychiatric and neurological disorders for which current treatments are mostly limited to pharmacotherapeutic interventions.
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spelling pubmed-84929062021-10-07 Replicating Cortical Signatures May Open the Possibility for “Transplanting” Brain States via Brain Entrainment Poltorak, Alexander Front Hum Neurosci Neuroscience Brain states, which correlate with specific motor, cognitive, and emotional states, may be monitored with noninvasive techniques such as electroencephalography (EEG) and magnetoencephalography (MEG) that measure macroscopic cortical activity manifested as oscillatory network dynamics. These rhythmic cortical signatures provide insight into the neuronal activity used to identify pathological cortical function in numerous neurological and psychiatric conditions. Sensory and transcranial stimulation, entraining the brain with specific brain rhythms, can effectively induce desired brain states (such as state of sleep or state of attention) correlated with such cortical rhythms. Because brain states have distinct neural correlates, it may be possible to induce a desired brain state by replicating these neural correlates through stimulation. To do so, we propose recording brain waves from a “donor” in a particular brain state using EEG/MEG to extract cortical signatures of the brain state. These cortical signatures would then be inverted and used to entrain the brain of a “recipient” via sensory or transcranial stimulation. We propose that brain states may thus be transferred between people by acquiring an associated cortical signature from a donor, which, following processing, may be applied to a recipient through sensory or transcranial stimulation. This technique may provide a novel and effective neuromodulation approach to the noninvasive, non-pharmacological treatment of a variety of psychiatric and neurological disorders for which current treatments are mostly limited to pharmacotherapeutic interventions. Frontiers Media S.A. 2021-09-22 /pmc/articles/PMC8492906/ /pubmed/34630058 http://dx.doi.org/10.3389/fnhum.2021.710003 Text en Copyright © 2021 Poltorak. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Poltorak, Alexander
Replicating Cortical Signatures May Open the Possibility for “Transplanting” Brain States via Brain Entrainment
title Replicating Cortical Signatures May Open the Possibility for “Transplanting” Brain States via Brain Entrainment
title_full Replicating Cortical Signatures May Open the Possibility for “Transplanting” Brain States via Brain Entrainment
title_fullStr Replicating Cortical Signatures May Open the Possibility for “Transplanting” Brain States via Brain Entrainment
title_full_unstemmed Replicating Cortical Signatures May Open the Possibility for “Transplanting” Brain States via Brain Entrainment
title_short Replicating Cortical Signatures May Open the Possibility for “Transplanting” Brain States via Brain Entrainment
title_sort replicating cortical signatures may open the possibility for “transplanting” brain states via brain entrainment
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492906/
https://www.ncbi.nlm.nih.gov/pubmed/34630058
http://dx.doi.org/10.3389/fnhum.2021.710003
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