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Gene Therapy Overexpressing Neuregulin 1 Type I in Combination With Neuregulin 1 Type III Promotes Functional Improvement in the SOD1(G93A) ALS Mice

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting the neuromuscular system for which currently there is no effective therapy. Motoneuron (MN) degeneration involves several complex mechanisms, including surrounding glial cells and skeletal muscle contributions. Neureg...

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Detalles Bibliográficos
Autores principales: Mòdol-Caballero, Guillem, Herrando-Grabulosa, Mireia, Verdés, Sergi, García-Lareu, Belén, Hernández, Neus, Francos-Quijorna, Isaac, López-Vales, Rubén, Bosch, Assumpció, Navarro, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492910/
https://www.ncbi.nlm.nih.gov/pubmed/34630277
http://dx.doi.org/10.3389/fneur.2021.693309