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Spt4 facilitates the movement of RNA polymerase II through the +2 nucleosomal barrier

Spt4 is a transcription elongation factor with homologs in organisms with nucleosomes. Structural and in vitro studies implicate Spt4 in transcription through nucleosomes, and yet the in vivo function of Spt4 is unclear. Here, we assess the precise position of Spt4 during transcription and the conse...

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Detalles Bibliográficos
Autores principales:	Uzun, Ülkü, Brown, Thomas, Fischl, Harry, Angel, Andrew, Mellor, Jane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492961/ https://www.ncbi.nlm.nih.gov/pubmed/34592154 http://dx.doi.org/10.1016/j.celrep.2021.109755

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