Bortezomib Inhibits Multiple Myeloma Cells by Transactivating ATF3 to Trigger miR-135a-5p- Dependent Apoptosis

Multiple myeloma (MM) is a malignant cancer with an increasing in incidence that can be alleviated through bortezomib (BTZ) treatment. Activating transcription factor 3 (ATF3) plays a major role in cancer development. Moreover, microRNAs (miRNAs) regulate carcinogenic pathways, apoptosis, and progra...

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Detalles Bibliográficos
Autores principales: Lai, Xiaolan, Huang, Chuanqian, Nie, Xuekun, Chen, Qi, Tang, Yirong, Fu, Xianguo, Lin, Ying, Nie, Chengjun, Xu, Xinyu, Wang, Xiukang, Chen, Renli, Chen, Zichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493032/
https://www.ncbi.nlm.nih.gov/pubmed/34631548
http://dx.doi.org/10.3389/fonc.2021.720261

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