Cargando…

RNA m1A Methyltransferase TRMT6 Predicts Poorer Prognosis and Promotes Malignant Behavior in Glioma

Background: Glioma is the most prevalent central nervous system tumor in humans, and its prognosis remains unsatisfactory due to a lack of effective therapeutic targets. The ectopic expression of N1-methyladenosine (m1A) regulators is a key participant in tumorigenesis and progression. However, the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Beibei, Niu, Lihua, Wang, Zhengyang, Zhao, Zhihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493077/ https://www.ncbi.nlm.nih.gov/pubmed/34631793 http://dx.doi.org/10.3389/fmolb.2021.692130

Ejemplares similares

Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B
por: Vilardo, Elisa, et al.
Publicado: (2020)

Integrative Genomic and Transcriptomic Analysis of Primary Malignant Gliomas Revealed Different Patterns Between Grades and Somatic Mutations Related to Glioblastoma Prognosis
por: Jin, Huawei, et al.
Publicado: (2022)

CD74 Correlated With Malignancies and Immune Microenvironment in Gliomas
por: Xu, Shengchao, et al.
Publicado: (2021)

Distinct substrate specificities of the human tRNA methyltransferases TRMT10A and TRMT10B
por: Howell, Nathan W., et al.
Publicado: (2019)

Methylation and Expression of the Exercise-Related TLR1 Gene Is Associated With Low Grade Glioma Prognosis and Outcome
por: Lu, Lichun, et al.
Publicado: (2021)

Decreased Expression of PACSIN1 in Brain Glioma Samples Predicts Poor Prognosis
por: Zimu, Zhou, et al.
Publicado: (2021)

Comprehensive Analysis Revealed the Potential Implications of m6A Regulators in Lung Adenocarcinoma
por: Xie, Lingling, et al.
Publicado: (2022)

Construction of m6A-based prognosis signature and prediction for immune and anti-angiogenic response
por: Wang, Xiang-Xu, et al.
Publicado: (2022)

A cuproptosis-related lncRNAs signature for prognosis, chemotherapy, and immune checkpoint blockade therapy of low-grade glioma
por: Yan, Xiuwei, et al.
Publicado: (2022)

CXCR4 is a Novel Biomarker Correlated With Malignant Transformation and Immune Infiltrates in Gastric Precancerous Lesions
por: Jiang, Xiaotao, et al.
Publicado: (2021)

m6A-Related lncRNAs Are Potential Biomarkers for the Prognosis of Metastatic Skin Cutaneous Melanoma
por: Huang, Suyang, et al.
Publicado: (2021)

Comprehensive Molecular Analyses of a Novel Mutational Signature Classification System with Regard to Prognosis, Genomic Alterations, and Immune Landscape in Glioma
por: Liu, Zaoqu, et al.
Publicado: (2021)

Comprehensive Analysis of HDAC Family Identifies HDAC1 as a Prognostic and Immune Infiltration Indicator and HDAC1-Related Signature for Prognosis in Glioma
por: Fan, Yuxiang, et al.
Publicado: (2021)

Characterization of METTL7B to Evaluate TME and Predict Prognosis by Integrative Analysis of Multi-Omics Data in Glioma
por: Chen, Xiaochuan, et al.
Publicado: (2021)

The N6-Methylandenosine-Related Gene BIRC5 as a Prognostic Biomarker Correlated With Cell Migration and Immune Cell Infiltrates in Low Grade Glioma
por: Jiang, Xiulin, et al.
Publicado: (2022)

The human 18S rRNA m(6)A methyltransferase METTL5 is stabilized by TRMT112
por: van Tran, Nhan, et al.
Publicado: (2019)

Identification and Validation of a Novel Three Hub Long Noncoding RNAs With m6A Modification Signature in Low-Grade Gliomas
por: Nguyen, Quang-Huy, et al.
Publicado: (2022)

A novel necroptosis-related gene signature for predict prognosis of glioma based on single-cell and bulk RNA sequencing
por: Guo, Kai, et al.
Publicado: (2022)

Arginine Methyltransferases as Regulators of RNA-Binding Protein Activities in Pathogenic Kinetoplastids
por: Campagnaro, Gustavo D., et al.
Publicado: (2021)

A B7-CD28 Family-Based Signature Demonstrates Significantly Different Prognosis and Immunological Characteristics in Diffuse Gliomas
por: Deng, Xiangyang, et al.
Publicado: (2022)

Comprehensive Analysis of mTORC1 Signaling Pathway–Related Genes in the Prognosis of HNSCC and the Response to Chemotherapy and Immunotherapy
por: Ding, Zhao, et al.
Publicado: (2022)

Six Metabolism Related mRNAs Predict the Prognosis of Patients With Hepatocellular Carcinoma
por: Wu, Xiwen, et al.
Publicado: (2021)

Williams-Beuren Syndrome Related Methyltransferase WBSCR27: From Structure to Possible Function
por: Mariasina, Sofia S., et al.
Publicado: (2022)

5-Methylcytosine RNA Methyltransferases-Related Long Non-coding RNA to Develop and Validate Biochemical Recurrence Signature in Prostate Cancer
por: Wang, Ke, et al.
Publicado: (2021)

Coexisting EGFR and TP53 Mutations in Lung Adenocarcinoma Patients Are Associated With COMP and ITGB8 Upregulation and Poor Prognosis
por: Zheng, Chang, et al.
Publicado: (2020)

Machine learning-based screening of an epithelial-mesenchymal transition-related long non-coding RNA signature reveals lower-grade glioma prognosis and the tumor microenvironment and predicts antitumor therapy response
por: Wang, Nan, et al.
Publicado: (2022)

Modification Patterns of DNA Methylation-Related lncRNAs Regulating Genomic Instability for Improving the Clinical Outcomes and Tumour Microenvironment Characterisation of Lower-Grade Gliomas
por: Maimaiti, Aierpati, et al.
Publicado: (2022)

Screening of ferroptosis-related genes with prognostic effect in colorectal cancer by bioinformatic analysis
por: Hu, Dongzhi, et al.
Publicado: (2022)

Identification of a Potential miRNA–mRNA Regulatory Network Associated With the Prognosis of HBV-ACLF
por: Ma, Shanshan, et al.
Publicado: (2021)

Upregulation of tRNA-Ser-AGA-2-1 Promotes Malignant Behavior in Normal Bronchial Cells
por: Santos, Mafalda, et al.
Publicado: (2022)

New Insights on Ferroptosis and Gynecological Malignancies
por: Fan, Ruiqi, et al.
Publicado: (2022)

Novel TrxR1 Inhibitors Show Potential for Glioma Treatment by Suppressing the Invasion and Sensitizing Glioma Cells to Chemotherapy
por: Jovanović, Mirna, et al.
Publicado: (2020)

Corrigendum: Identification of a Potential miRNA-mRNA Regulatory Network Associated With the Prognosis of HBV-ACLF
por: Ma, Shanshan, et al.
Publicado: (2021)

Regulation of Cholesterol Binding to the Receptor Patched1 by its interactions With the Ligand Sonic Hedgehog (Shh)
por: Zhong, Changqing, et al.
Publicado: (2022)

SEMA6B Overexpression Predicts Poor Prognosis and Correlates With the Tumor Immunosuppressive Microenvironment in Colorectal Cancer
por: Li, Tiegang, et al.
Publicado: (2021)

Prognostic Potential of Secreted Modular Calcium-Binding Protein 1 in Low-Grade Glioma
por: Wang, Jing, et al.
Publicado: (2021)

Identification of a Novel Protein-Based Signature to Improve Prognosis Prediction in Renal Clear Cell Carcinoma
por: Chu, Guangdi, et al.
Publicado: (2021)

Gut microbiota-dependent adaptor molecule recruits DNA methyltransferase to the TLR4 gene in colonic epithelial cells to suppress inflammatory reactions
por: Narabayashi, Hikari, et al.
Publicado: (2022)

Identification of Prognostic Biomarkers in Patients With Malignant Rhabdoid Tumor of the Kidney Based on mTORC1 Signaling Pathway-Related Genes
por: Zhanghuang, Chenghao, et al.
Publicado: (2022)

Overexpressed CMTM6 Improves Prognosis and Associated With Immune Infiltrates of Ovarian Cancer
por: Yin, Bo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pdb6f51tsa68opr0pp14a83gr7