Clinical experience with a new injectable hyaluronic acid designed to improve skin quality in a private clinic in Brazil: A retrospective cohort study

BACKGROUND: Juvéderm Volite is a skin‐conditioning hyaluronic acid (HA) gel for intradermal injection that provides longer‐lasting effects with a lower concentration of hyaluronic acid. Few studies evaluating its use for aesthetic purposes are available. AIM: To examine the use and safety of Juvéderm Volite in daily clinical practice. METHODS: A retrospective cohort study of subjects treated with Juvéderm Volite for aesthetic purposes from May 2018 to October 2019 in Rio de Janeiro. Data were extracted from the attending physician's records obtained at each medical appointment. Subjects were assessed according to their age group and treatment characteristics, which include the use of cannulas vs needles and the effectiveness and safety of associated treatments in a single session. Need for subsequent treatment was stratified by touch‐up treatment (<3‐month period) and repeat treatment (≥3‐month period). Safety assessment was based on the report of nodule formation and late hypersensitivity in patients. Appropriate statistical tests were used for data analysis. RESULTS: One hundred and eight subjects were included in the study analysis. The total number of treatment sessions consisted of 159, with a mean follow‐up time of 300.3 days. Of the total 108 subjects, 8.4% required touch‐up treatment for optimum correction and repeat treatment occurred in 9.0%. No cases of adverse events were reported during the follow‐up period. CONCLUSIONS: This study has shown, based on clinical observation, that Juvéderm Volite is a useful tool to improve skin quality, requiring fewer and less frequent maintenance treatments. No serious adverse events were reported during the follow‐up period.