Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations

Elicitation of broadly neutralizing antibodies (bnAbs) by an HIV vaccine will involve priming the immune system to activate antibody precursors, followed by boosting immunizations to select for antibodies with functional features required for neutralization breadth. The higher the number of acquired...

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Detalles Bibliográficos
Autores principales: Swanson, Olivia, Rhodes, Brianna, Wang, Avivah, Xia, Shi-Mao, Parks, Robert, Chen, Haiyan, Sanzone, Aja, Cooper, Melissa, Louder, Mark K., Lin, Bob C., Doria-Rose, Nicole A., Bonsignori, Mattia, Saunders, Kevin O., Wiehe, Kevin, Haynes, Barton F., Azoitei, Mihai L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493474/
https://www.ncbi.nlm.nih.gov/pubmed/34407396
http://dx.doi.org/10.1016/j.celrep.2021.109561

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