Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides

[Image: see text] Telomerase represents an attractive target in oncology as it is expressed in cancer but not in normal tissues. The oligonucleotide inhibitors of telomerase represent a promising anticancer strategy, although poor cellular uptake can restrict their efficacy. In this study, gold nano...

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Detalles Bibliográficos
Autores principales: Bavelaar, Bas M., Song, Lei, Jackson, Mark R., Able, Sarah, Tietz, Ole, Skaripa-Koukelli, Irini, Waghorn, Philip A., Gill, Martin R., Carlisle, Robert C., Tarsounas, Madalena, Vallis, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493550/
https://www.ncbi.nlm.nih.gov/pubmed/34449222
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00442

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