Mutant NPM1-regulated lncRNA HOTAIRM1 promotes leukemia cell autophagy and proliferation by targeting EGR1 and ULK3

BACKGROUND: Acute myeloid leukemia (AML) with mutated nucleophosmin (NPM1), which displays a distinct long noncoding RNA (lncRNA) expression profile, has been defined as a unique subgroup in the new classification of myeloid neoplasms. However, the biological roles of key lncRNAs in the development...

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Detalles Bibliográficos
Autores principales: Jing, Yipei, Jiang, Xueke, Lei, Li, Peng, Meixi, Ren, Jun, Xiao, Qiaoling, Tao, Yao, Tao, Yonghong, Huang, Junpeng, Wang, Lu, Tang, Yuting, Yang, Zailin, Yang, Zesong, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493742/
https://www.ncbi.nlm.nih.gov/pubmed/34615546
http://dx.doi.org/10.1186/s13046-021-02122-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493742/
https://www.ncbi.nlm.nih.gov/pubmed/34615546
http://dx.doi.org/10.1186/s13046-021-02122-2

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