ROCK inhibitors modulate the physical properties and adipogenesis of 3D spheroids of human orbital fibroblasts in different manners

To elucidate the pharmacological effects of Rho‐associated coiled‐coil containing protein kinase inhibitors (ROCK‐is), ripasudil (Rip), Y27632, and KD025, on human orbital fatty tissue, the human orbital fibroblasts (HOFs) were three‐dimensional (3D) cultured for 12 days. The effects of ROCK‐is on t...

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Detalles Bibliográficos
Autores principales: Hikage, Fumihito, Ichioka, Hanae, Watanabe, Megumi, Umetsu, Araya, Ohguro, Hiroshi, Ida, Yosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493964/
https://www.ncbi.nlm.nih.gov/pubmed/34632320
http://dx.doi.org/10.1096/fba.2021-00037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493964/
https://www.ncbi.nlm.nih.gov/pubmed/34632320
http://dx.doi.org/10.1096/fba.2021-00037

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