Identifying susceptibility genes for primary ovarian insufficiency on the high-risk genetic background of a fragile X premutation

OBJECTIVE: To identify modifying genes that explains the risk of fragile X-associated primary ovarian insufficiency (FXPOI). DESIGN: Gene-based, case/control association study, followed by a functional screen of highly ranked genes using a Drosophila model. SETTING: Participants were recruited from...

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Detalles Bibliográficos
Autores principales: Trevino, Cristina E., Rounds, J. Christopher, Charen, Krista, Shubeck, Lisa, Hipp, Heather S., Spencer, Jessica B., Johnston, H. Richard, Cutler, Dave J., Zwick, Michael E., Epstein, Michael P., Murray, Anna, Macpherson, James N., Mila, Montserrat, Rodriguez-Revenga, Laia, Berry-Kravis, Elizabeth, Hall, Deborah A., Leehey, Maureen A., Liu, Ying, Welt, Corrine, Warren, Stephen T., Sherman, Stephanie L., Jin, Peng, Allen, Emily G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494118/
https://www.ncbi.nlm.nih.gov/pubmed/34016428
http://dx.doi.org/10.1016/j.fertnstert.2021.04.021

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