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Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome
Aldosterone is a mineralocorticoid hormone that maintains sodium and potassium homeostasis. Excess aldosterone secretion causes sodium influx and potassium outflow, leading to hypertension and in some cases hypokalemia. Conn's syndrome, or primary aldosteronism, is the most common cause of seco...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494148/ https://www.ncbi.nlm.nih.gov/pubmed/34659984 http://dx.doi.org/10.7759/cureus.17773 |
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author | Ganta, Nagapratap Choe, Suhrim Kanukuntla, Anish Kata, Priyaranjan Cheriyath, Pramil |
author_facet | Ganta, Nagapratap Choe, Suhrim Kanukuntla, Anish Kata, Priyaranjan Cheriyath, Pramil |
author_sort | Ganta, Nagapratap |
collection | PubMed |
description | Aldosterone is a mineralocorticoid hormone that maintains sodium and potassium homeostasis. Excess aldosterone secretion causes sodium influx and potassium outflow, leading to hypertension and in some cases hypokalemia. Conn's syndrome, or primary aldosteronism, is the most common cause of secondary hypertension, accounting for 20% or more of people with resistant hypertension. We present a young male with hypertension, blurry vision in the right eye, and hypokalemia who was on further investigation found to have an aldosterone-secreting adrenal adenoma. He was treated with retroperitoneoscopic right-sided adrenalectomy and his blood pressure improved. Conn's syndrome should be suspected in any hypertensive patient with hypokalemia. Adrenal venous sampling is the best investigation to measure aldosterone levels and also to lateralize the source. Surgical resection is the treatment of choice. |
format | Online Article Text |
id | pubmed-8494148 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-84941482021-10-14 Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome Ganta, Nagapratap Choe, Suhrim Kanukuntla, Anish Kata, Priyaranjan Cheriyath, Pramil Cureus Cardiology Aldosterone is a mineralocorticoid hormone that maintains sodium and potassium homeostasis. Excess aldosterone secretion causes sodium influx and potassium outflow, leading to hypertension and in some cases hypokalemia. Conn's syndrome, or primary aldosteronism, is the most common cause of secondary hypertension, accounting for 20% or more of people with resistant hypertension. We present a young male with hypertension, blurry vision in the right eye, and hypokalemia who was on further investigation found to have an aldosterone-secreting adrenal adenoma. He was treated with retroperitoneoscopic right-sided adrenalectomy and his blood pressure improved. Conn's syndrome should be suspected in any hypertensive patient with hypokalemia. Adrenal venous sampling is the best investigation to measure aldosterone levels and also to lateralize the source. Surgical resection is the treatment of choice. Cureus 2021-09-06 /pmc/articles/PMC8494148/ /pubmed/34659984 http://dx.doi.org/10.7759/cureus.17773 Text en Copyright © 2021, Ganta et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Ganta, Nagapratap Choe, Suhrim Kanukuntla, Anish Kata, Priyaranjan Cheriyath, Pramil Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome |
title | Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome |
title_full | Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome |
title_fullStr | Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome |
title_full_unstemmed | Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome |
title_short | Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome |
title_sort | hypertensive emergency in a young patient with unilateral adrenal hyperplasia: a case of conn's syndrome |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494148/ https://www.ncbi.nlm.nih.gov/pubmed/34659984 http://dx.doi.org/10.7759/cureus.17773 |
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