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Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome

Aldosterone is a mineralocorticoid hormone that maintains sodium and potassium homeostasis. Excess aldosterone secretion causes sodium influx and potassium outflow, leading to hypertension and in some cases hypokalemia. Conn's syndrome, or primary aldosteronism, is the most common cause of seco...

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Autores principales: Ganta, Nagapratap, Choe, Suhrim, Kanukuntla, Anish, Kata, Priyaranjan, Cheriyath, Pramil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494148/
https://www.ncbi.nlm.nih.gov/pubmed/34659984
http://dx.doi.org/10.7759/cureus.17773
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author Ganta, Nagapratap
Choe, Suhrim
Kanukuntla, Anish
Kata, Priyaranjan
Cheriyath, Pramil
author_facet Ganta, Nagapratap
Choe, Suhrim
Kanukuntla, Anish
Kata, Priyaranjan
Cheriyath, Pramil
author_sort Ganta, Nagapratap
collection PubMed
description Aldosterone is a mineralocorticoid hormone that maintains sodium and potassium homeostasis. Excess aldosterone secretion causes sodium influx and potassium outflow, leading to hypertension and in some cases hypokalemia. Conn's syndrome, or primary aldosteronism, is the most common cause of secondary hypertension, accounting for 20% or more of people with resistant hypertension. We present a young male with hypertension, blurry vision in the right eye, and hypokalemia who was on further investigation found to have an aldosterone-secreting adrenal adenoma. He was treated with retroperitoneoscopic right-sided adrenalectomy and his blood pressure improved. Conn's syndrome should be suspected in any hypertensive patient with hypokalemia. Adrenal venous sampling is the best investigation to measure aldosterone levels and also to lateralize the source. Surgical resection is the treatment of choice.
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spelling pubmed-84941482021-10-14 Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome Ganta, Nagapratap Choe, Suhrim Kanukuntla, Anish Kata, Priyaranjan Cheriyath, Pramil Cureus Cardiology Aldosterone is a mineralocorticoid hormone that maintains sodium and potassium homeostasis. Excess aldosterone secretion causes sodium influx and potassium outflow, leading to hypertension and in some cases hypokalemia. Conn's syndrome, or primary aldosteronism, is the most common cause of secondary hypertension, accounting for 20% or more of people with resistant hypertension. We present a young male with hypertension, blurry vision in the right eye, and hypokalemia who was on further investigation found to have an aldosterone-secreting adrenal adenoma. He was treated with retroperitoneoscopic right-sided adrenalectomy and his blood pressure improved. Conn's syndrome should be suspected in any hypertensive patient with hypokalemia. Adrenal venous sampling is the best investigation to measure aldosterone levels and also to lateralize the source. Surgical resection is the treatment of choice. Cureus 2021-09-06 /pmc/articles/PMC8494148/ /pubmed/34659984 http://dx.doi.org/10.7759/cureus.17773 Text en Copyright © 2021, Ganta et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Ganta, Nagapratap
Choe, Suhrim
Kanukuntla, Anish
Kata, Priyaranjan
Cheriyath, Pramil
Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome
title Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome
title_full Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome
title_fullStr Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome
title_full_unstemmed Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome
title_short Hypertensive Emergency in a Young Patient With Unilateral Adrenal Hyperplasia: A Case of Conn's Syndrome
title_sort hypertensive emergency in a young patient with unilateral adrenal hyperplasia: a case of conn's syndrome
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494148/
https://www.ncbi.nlm.nih.gov/pubmed/34659984
http://dx.doi.org/10.7759/cureus.17773
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