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Retrobulbar Hemorrhage Secondary to Acquired Hemophilia A

Acquired hemophilia A (AHA) is a different bleeding disorder to that of classic hemophilia A. It is an autoimmune-mediated bleeding disorder due to the presence of autoantibodies (inhibitors) directed against plasma coagulation factor VIII. This can result in fatal hemorrhage; thus, eradication of t...

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Autores principales: Jayasundara, Hishali D, Herath, Lasitha Y, Kularatne, Keertie S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494152/
https://www.ncbi.nlm.nih.gov/pubmed/34659972
http://dx.doi.org/10.7759/cureus.17760
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author Jayasundara, Hishali D
Herath, Lasitha Y
Kularatne, Keertie S
author_facet Jayasundara, Hishali D
Herath, Lasitha Y
Kularatne, Keertie S
author_sort Jayasundara, Hishali D
collection PubMed
description Acquired hemophilia A (AHA) is a different bleeding disorder to that of classic hemophilia A. It is an autoimmune-mediated bleeding disorder due to the presence of autoantibodies (inhibitors) directed against plasma coagulation factor VIII. This can result in fatal hemorrhage; thus, eradication of the antibody is the mainstay of treatment. Nontraumatic retrobulbar hemorrhage is a very rare presentation of hemophilia. We report an elderly male presenting with retrobulbar hemorrhage secondary to AHA who was successfully treated with immunosuppression.
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spelling pubmed-84941522021-10-14 Retrobulbar Hemorrhage Secondary to Acquired Hemophilia A Jayasundara, Hishali D Herath, Lasitha Y Kularatne, Keertie S Cureus Dermatology Acquired hemophilia A (AHA) is a different bleeding disorder to that of classic hemophilia A. It is an autoimmune-mediated bleeding disorder due to the presence of autoantibodies (inhibitors) directed against plasma coagulation factor VIII. This can result in fatal hemorrhage; thus, eradication of the antibody is the mainstay of treatment. Nontraumatic retrobulbar hemorrhage is a very rare presentation of hemophilia. We report an elderly male presenting with retrobulbar hemorrhage secondary to AHA who was successfully treated with immunosuppression. Cureus 2021-09-06 /pmc/articles/PMC8494152/ /pubmed/34659972 http://dx.doi.org/10.7759/cureus.17760 Text en Copyright © 2021, Jayasundara et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Jayasundara, Hishali D
Herath, Lasitha Y
Kularatne, Keertie S
Retrobulbar Hemorrhage Secondary to Acquired Hemophilia A
title Retrobulbar Hemorrhage Secondary to Acquired Hemophilia A
title_full Retrobulbar Hemorrhage Secondary to Acquired Hemophilia A
title_fullStr Retrobulbar Hemorrhage Secondary to Acquired Hemophilia A
title_full_unstemmed Retrobulbar Hemorrhage Secondary to Acquired Hemophilia A
title_short Retrobulbar Hemorrhage Secondary to Acquired Hemophilia A
title_sort retrobulbar hemorrhage secondary to acquired hemophilia a
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494152/
https://www.ncbi.nlm.nih.gov/pubmed/34659972
http://dx.doi.org/10.7759/cureus.17760
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