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An atomistic model of the coronavirus replication-transcription complex as a hexamer assembled around nsp15

The SARS-CoV-2 replication-transcription complex is an assembly of nonstructural viral proteins that collectively act to reproduce the viral genome and generate mRNA transcripts. While the structures of the individual proteins involved are known, how they assemble into a functioning superstructure i...

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Detalles Bibliográficos
Autores principales:	Perry, Jason K., Appleby, Todd C., Bilello, John P., Feng, Joy Y., Schmitz, Uli, Campbell, Elizabeth A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494237/ https://www.ncbi.nlm.nih.gov/pubmed/34562452 http://dx.doi.org/10.1016/j.jbc.2021.101218

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