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A Chinese survey on clinical practice in hyperthyroidism management: comparison with recent studies and guidelines

OBJECTIVE: To conduct a questionnaire survey of the current clinical practice for overt hyperthyroidism in China. METHODS: An online questionnaire survey was conducted in July 2020. The two questionnaires covered 35 and 8 questions about non-pregnancy and pregnancy clinical practice for overt hypert...

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Autores principales: Wang, Xichang, Teng, Xiaochun, Li, Chenyan, Li, Yushu, Li, Jing, Teng, Weiping, Shan, Zhongyan, Lai, Yaxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494401/
https://www.ncbi.nlm.nih.gov/pubmed/34382578
http://dx.doi.org/10.1530/EC-21-0340
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author Wang, Xichang
Teng, Xiaochun
Li, Chenyan
Li, Yushu
Li, Jing
Teng, Weiping
Shan, Zhongyan
Lai, Yaxin
author_facet Wang, Xichang
Teng, Xiaochun
Li, Chenyan
Li, Yushu
Li, Jing
Teng, Weiping
Shan, Zhongyan
Lai, Yaxin
author_sort Wang, Xichang
collection PubMed
description OBJECTIVE: To conduct a questionnaire survey of the current clinical practice for overt hyperthyroidism in China. METHODS: An online questionnaire survey was conducted in July 2020. The two questionnaires covered 35 and 8 questions about non-pregnancy and pregnancy clinical practice for overt hyperthyroidism, respectively. RESULTS: One thousand, two hundred fifty-six physicians participated. Chief physicians and associate chief physicians accounted for 58.6% of the participants. Approximately 95.2% of the respondents chose the thyrotropin receptor antibody (TRAb) test to clarify the etiology of thyrotoxicosis, while only 27.0% of them chose radioactive iodine uptake (RAIU). In terms of treatment for non-pregnant patients, anti-thyroid drugs (ATDs) were the first choice, and most of the clinicians chose methimazole. Compared with clinicians in recent studies, Chinese physicians used serum TRAb to diagnose Graves’ disease more commonly, and there were obviously more physicians preferring ATDs. For maternal hyperthyroidism, most physicians preferred propylthiouracil administration before or during the first trimester, which is consistent with the 2016 American Thyroid Association (ATA) guidelines. In terms of the initial ATD dose, monitoring the treatment process, indications for ATD withdrawal and treatment of special cases, the preferences of Chinese physicians were generally consistent with the guidelines. CONCLUSION: Chinese physicians can generally follow the ATA guidelines for the diagnosis and treatment of hyperthyroidism. Moreover, there are small differences from foreign studies or the guidelines with respect to particular problems. These findings provide evidence for future clinical research in China.
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spelling pubmed-84944012021-10-12 A Chinese survey on clinical practice in hyperthyroidism management: comparison with recent studies and guidelines Wang, Xichang Teng, Xiaochun Li, Chenyan Li, Yushu Li, Jing Teng, Weiping Shan, Zhongyan Lai, Yaxin Endocr Connect Research OBJECTIVE: To conduct a questionnaire survey of the current clinical practice for overt hyperthyroidism in China. METHODS: An online questionnaire survey was conducted in July 2020. The two questionnaires covered 35 and 8 questions about non-pregnancy and pregnancy clinical practice for overt hyperthyroidism, respectively. RESULTS: One thousand, two hundred fifty-six physicians participated. Chief physicians and associate chief physicians accounted for 58.6% of the participants. Approximately 95.2% of the respondents chose the thyrotropin receptor antibody (TRAb) test to clarify the etiology of thyrotoxicosis, while only 27.0% of them chose radioactive iodine uptake (RAIU). In terms of treatment for non-pregnant patients, anti-thyroid drugs (ATDs) were the first choice, and most of the clinicians chose methimazole. Compared with clinicians in recent studies, Chinese physicians used serum TRAb to diagnose Graves’ disease more commonly, and there were obviously more physicians preferring ATDs. For maternal hyperthyroidism, most physicians preferred propylthiouracil administration before or during the first trimester, which is consistent with the 2016 American Thyroid Association (ATA) guidelines. In terms of the initial ATD dose, monitoring the treatment process, indications for ATD withdrawal and treatment of special cases, the preferences of Chinese physicians were generally consistent with the guidelines. CONCLUSION: Chinese physicians can generally follow the ATA guidelines for the diagnosis and treatment of hyperthyroidism. Moreover, there are small differences from foreign studies or the guidelines with respect to particular problems. These findings provide evidence for future clinical research in China. Bioscientifica Ltd 2021-08-11 /pmc/articles/PMC8494401/ /pubmed/34382578 http://dx.doi.org/10.1530/EC-21-0340 Text en © The authors https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Research
Wang, Xichang
Teng, Xiaochun
Li, Chenyan
Li, Yushu
Li, Jing
Teng, Weiping
Shan, Zhongyan
Lai, Yaxin
A Chinese survey on clinical practice in hyperthyroidism management: comparison with recent studies and guidelines
title A Chinese survey on clinical practice in hyperthyroidism management: comparison with recent studies and guidelines
title_full A Chinese survey on clinical practice in hyperthyroidism management: comparison with recent studies and guidelines
title_fullStr A Chinese survey on clinical practice in hyperthyroidism management: comparison with recent studies and guidelines
title_full_unstemmed A Chinese survey on clinical practice in hyperthyroidism management: comparison with recent studies and guidelines
title_short A Chinese survey on clinical practice in hyperthyroidism management: comparison with recent studies and guidelines
title_sort chinese survey on clinical practice in hyperthyroidism management: comparison with recent studies and guidelines
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494401/
https://www.ncbi.nlm.nih.gov/pubmed/34382578
http://dx.doi.org/10.1530/EC-21-0340
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