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A Conserved Gcn2-Gcn4 Axis Links Methionine Utilization and the Oxidative Stress Response in Cryptococcus neoformans

The fungal pathogen Cryptococcus neoformans relies on post-transcriptional mechanisms of gene regulation to adapt to stressors it encounters in the human host, such as oxidative stress and nutrient limitation. The kinase Gcn2 regulates translation in response to stress by phosphorylating the initiat...

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Detalles Bibliográficos
Autores principales: Stovall, Anna K., Knowles, Corey M., Kalem, Murat C., Panepinto, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494424/
https://www.ncbi.nlm.nih.gov/pubmed/34622246
http://dx.doi.org/10.3389/ffunb.2021.640678