Development of a fluorogenic ADAMTS-7 substrate

The extracellular protease ADAMTS-7 has been identified as a potential therapeutic target in atherosclerosis and associated diseases such as coronary artery disease (CAD). However, ADAMTS-7 inhibitors have not been reported so far. Screening of inhibitors has been hindered by the lack of a suitable...

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Detalles Bibliográficos
Autores principales: Santamaria, Salvatore, Buemi, Frederic, Nuti, Elisa, Cuffaro, Doretta, De Vita, Elena, Tuccinardi, Tiziano, Rossello, Armando, Howell, Steven, Mehmood, Shahid, Snijders, Ambrosius P., de Groot, Rens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494430/
https://www.ncbi.nlm.nih.gov/pubmed/34587841
http://dx.doi.org/10.1080/14756366.2021.1983808

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