Cargando…
Learning delay dynamics for multivariate stochastic processes, with application to the prediction of the growth rate of COVID-19 cases in the United States()
Delay differential equations form the underpinning of many complex dynamical systems. The forward problem of solving random differential equations with delay has received increasing attention in recent years. Motivated by the challenge to predict the COVID-19 caseload trajectories for individual sta...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494512/ https://www.ncbi.nlm.nih.gov/pubmed/34642503 http://dx.doi.org/10.1016/j.jmaa.2021.125677 |
_version_ | 1784579326041128960 |
---|---|
author | Dubey, Paromita Chen, Yaqing Gajardo, Álvaro Bhattacharjee, Satarupa Carroll, Cody Zhou, Yidong Chen, Han Müller, Hans-Georg |
author_facet | Dubey, Paromita Chen, Yaqing Gajardo, Álvaro Bhattacharjee, Satarupa Carroll, Cody Zhou, Yidong Chen, Han Müller, Hans-Georg |
author_sort | Dubey, Paromita |
collection | PubMed |
description | Delay differential equations form the underpinning of many complex dynamical systems. The forward problem of solving random differential equations with delay has received increasing attention in recent years. Motivated by the challenge to predict the COVID-19 caseload trajectories for individual states in the U.S., we target here the inverse problem. Given a sample of observed random trajectories obeying an unknown random differential equation model with delay, we use a functional data analysis framework to learn the model parameters that govern the underlying dynamics from the data. We show the existence and uniqueness of the analytical solutions of the population delay random differential equation model when one has discrete time delays in the functional concurrent regression model and also for a second scenario where one has a delay continuum or distributed delay. The latter involves a functional linear regression model with history index. The derivative of the process of interest is modeled using the process itself as predictor and also other functional predictors with predictor-specific delayed impacts. This dynamics learning approach is shown to be well suited to model the growth rate of COVID-19 for the states that are part of the U.S., by pooling information from the individual states, using the case process and concurrently observed economic and mobility data as predictors. |
format | Online Article Text |
id | pubmed-8494512 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84945122021-10-08 Learning delay dynamics for multivariate stochastic processes, with application to the prediction of the growth rate of COVID-19 cases in the United States() Dubey, Paromita Chen, Yaqing Gajardo, Álvaro Bhattacharjee, Satarupa Carroll, Cody Zhou, Yidong Chen, Han Müller, Hans-Georg J Math Anal Appl Article Delay differential equations form the underpinning of many complex dynamical systems. The forward problem of solving random differential equations with delay has received increasing attention in recent years. Motivated by the challenge to predict the COVID-19 caseload trajectories for individual states in the U.S., we target here the inverse problem. Given a sample of observed random trajectories obeying an unknown random differential equation model with delay, we use a functional data analysis framework to learn the model parameters that govern the underlying dynamics from the data. We show the existence and uniqueness of the analytical solutions of the population delay random differential equation model when one has discrete time delays in the functional concurrent regression model and also for a second scenario where one has a delay continuum or distributed delay. The latter involves a functional linear regression model with history index. The derivative of the process of interest is modeled using the process itself as predictor and also other functional predictors with predictor-specific delayed impacts. This dynamics learning approach is shown to be well suited to model the growth rate of COVID-19 for the states that are part of the U.S., by pooling information from the individual states, using the case process and concurrently observed economic and mobility data as predictors. Elsevier Inc. 2022-10-15 2021-09-28 /pmc/articles/PMC8494512/ /pubmed/34642503 http://dx.doi.org/10.1016/j.jmaa.2021.125677 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Dubey, Paromita Chen, Yaqing Gajardo, Álvaro Bhattacharjee, Satarupa Carroll, Cody Zhou, Yidong Chen, Han Müller, Hans-Georg Learning delay dynamics for multivariate stochastic processes, with application to the prediction of the growth rate of COVID-19 cases in the United States() |
title | Learning delay dynamics for multivariate stochastic processes, with application to the prediction of the growth rate of COVID-19 cases in the United States() |
title_full | Learning delay dynamics for multivariate stochastic processes, with application to the prediction of the growth rate of COVID-19 cases in the United States() |
title_fullStr | Learning delay dynamics for multivariate stochastic processes, with application to the prediction of the growth rate of COVID-19 cases in the United States() |
title_full_unstemmed | Learning delay dynamics for multivariate stochastic processes, with application to the prediction of the growth rate of COVID-19 cases in the United States() |
title_short | Learning delay dynamics for multivariate stochastic processes, with application to the prediction of the growth rate of COVID-19 cases in the United States() |
title_sort | learning delay dynamics for multivariate stochastic processes, with application to the prediction of the growth rate of covid-19 cases in the united states() |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494512/ https://www.ncbi.nlm.nih.gov/pubmed/34642503 http://dx.doi.org/10.1016/j.jmaa.2021.125677 |
work_keys_str_mv | AT dubeyparomita learningdelaydynamicsformultivariatestochasticprocesseswithapplicationtothepredictionofthegrowthrateofcovid19casesintheunitedstates AT chenyaqing learningdelaydynamicsformultivariatestochasticprocesseswithapplicationtothepredictionofthegrowthrateofcovid19casesintheunitedstates AT gajardoalvaro learningdelaydynamicsformultivariatestochasticprocesseswithapplicationtothepredictionofthegrowthrateofcovid19casesintheunitedstates AT bhattacharjeesatarupa learningdelaydynamicsformultivariatestochasticprocesseswithapplicationtothepredictionofthegrowthrateofcovid19casesintheunitedstates AT carrollcody learningdelaydynamicsformultivariatestochasticprocesseswithapplicationtothepredictionofthegrowthrateofcovid19casesintheunitedstates AT zhouyidong learningdelaydynamicsformultivariatestochasticprocesseswithapplicationtothepredictionofthegrowthrateofcovid19casesintheunitedstates AT chenhan learningdelaydynamicsformultivariatestochasticprocesseswithapplicationtothepredictionofthegrowthrateofcovid19casesintheunitedstates AT mullerhansgeorg learningdelaydynamicsformultivariatestochasticprocesseswithapplicationtothepredictionofthegrowthrateofcovid19casesintheunitedstates |