A Practical, One-Clinic Visit Protocol for Pharmacokinetic Profile Generation with the ADVATE myPKFiT Dosing Tool in Severe Hemophilia A Subjects

Standard pharmacokinetic (PK) assessments are demanding for persons with hemophilia A, requiring a 72-hour washout and 5 to 11 timed blood samples. A no-washout, single-clinic visit, sparse sampling population PK (PPK) protocol is an attractive alternative. Here, we compared PK parameters obtained w...

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Detalles Bibliográficos
Autores principales: Blanchette, Victor S., Zunino, Laura, Grassmann, Viviane, Barnes, Chris, Carcao, Manuel D., Curtin, Julie, Jackson, Shannon, Khoo, Liane, Komrska, Vladimir, Lillicrap, David, Morfini, Massimo, Romanova, Gabriela, Stephens, Derek, Zapotocka, Ester, Rand, Margaret L., Blatny, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494515/
https://www.ncbi.nlm.nih.gov/pubmed/33506480
http://dx.doi.org/10.1055/a-1376-0970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494515/
https://www.ncbi.nlm.nih.gov/pubmed/33506480
http://dx.doi.org/10.1055/a-1376-0970

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