Cargando…

Thyroid Transcription Factor-1: Structure, Expression, Function and Its Relationship with Disease

Thyroid transcription factor-1 (TTF-1/NKx2.1) is a member of the NKx2 tissue-specific transcription factor family, which is expressed in thyroid follicle, parathyroid gland, alveolar epithelium, and diencephalon which originated from ectoderm, and participates in the differentiation, development, an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guan, Lian, Zhao, Xu, Tang, Lin, Chen, Jing, Zhao, Juanjuan, Guo, Mengmeng, Chen, Chao, Zhou, Ya, Xu, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494563/ https://www.ncbi.nlm.nih.gov/pubmed/34631891 http://dx.doi.org/10.1155/2021/9957209

Ejemplares similares

DUSP8 phosphatase: structure, functions, expression regulation and the role in human diseases
por: Ding, Tao, et al.
Publicado: (2019)

MicroRNA-7: expression and function in brain physiological and pathological processes
por: Zhao, Juanjuan, et al.
Publicado: (2020)

Mechanisms Controlling MicroRNA Expression in Tumor
por: Chen, Shipeng, et al.
Publicado: (2022)

MicroRNAs expression profile in CCR6(+) regulatory T cells
por: Zhao, Juanjuan, et al.
Publicado: (2014)

MicroRNA-7, synergizes with RORα, negatively controls the pathology of brain tissue inflammation
por: Yue, Dongxu, et al.
Publicado: (2020)

Targeted Expression of miR-7 Operated by TTF-1 Promoter Inhibited the Growth of Human Lung Cancer through the NDUFA4 Pathway
por: Lei, Liangyu, et al.
Publicado: (2017)

Let-7 as a Promising Target in Aging and Aging-Related Diseases: A Promise or a Pledge
por: Wang, Ya, et al.
Publicado: (2022)

MicroRNA-7: A New Intervention Target for Inflammation and Related Diseases
por: Chen, Chao, et al.
Publicado: (2023)

The role and its mechanism of intermittent fasting in tumors: friend or foe?
por: Zhao, Xu, et al.
Publicado: (2021)

Antisense Oligonucleotides against miR-21 Inhibit the Growth and Metastasis of Colorectal Carcinoma via the DUSP8 Pathway
por: Ding, Tao, et al.
Publicado: (2018)

MicroRNA-7 Deficiency Ameliorates the Pathologies of Acute Lung Injury through Elevating KLF4
por: Zhao, Juanjuan, et al.
Publicado: (2016)

The Role of MicroRNAs in Aβ Deposition and Tau Phosphorylation in Alzheimer’s Disease
por: Zhao, Juanjuan, et al.
Publicado: (2017)

Identification of atypical mitogen-activated protein kinase MAPK4 as a novel regulator in acute lung injury
por: Mao, Ling, et al.
Publicado: (2020)

MiRNA-Based Therapies for Lung Cancer: Opportunities and Challenges?
por: Yang, Han, et al.
Publicado: (2023)

Assessing maternal thyroid function and its relationship to duration of the first stage of labor
por: Wei, Hongcheng, et al.
Publicado: (2022)

The prognostic value of miR-126 expression in non-small-cell lung cancer: a meta-analysis
por: Zheng, Wen, et al.
Publicado: (2017)

T Helper 9 Cells: A New Player in Immune-Related Diseases
por: Chen, Jing, et al.
Publicado: (2019)

Effect of FOXP2 transcription factor on immune infiltration of thyroid cancer and its potential clinical value
por: Xu, Lianghui, et al.
Publicado: (2022)

TCR repertoire landscape reveals macrophage-mediated clone deletion in endotoxin tolerance
por: Zhao, Juanjuan, et al.
Publicado: (2023)

Serum resolvin E1 levels and its relationship with thyroid autoimmunity in Hashimoto’s thyroiditis: a preliminary study
por: Song, Jing, et al.
Publicado: (2021)

The relationships between thyroid functions of short-term rapid hypothyroidism and blood lipid levels in post-thyroidectomy patients of differentiated thyroid cancer
por: Yao, Jinming, et al.
Publicado: (2023)

MicroRNA-126: A new and promising player in lung cancer
por: Chen, Qijun, et al.
Publicado: (2021)

MicroRNA-7: a promising new target in cancer therapy
por: Zhao, Juanjuan, et al.
Publicado: (2015)

Identification of a secondary promoter of CASP8 and its related transcription factor PURα
por: LIN, ZHENGWEI, et al.
Publicado: (2014)

Promoter-Operating Targeted Expression of Gene Therapy in Cancer: Current Stage and Prospect
por: Chen, Chao, et al.
Publicado: (2018)

Thyroid transcription factor-1 expression is significantly associated with mutations in exon 21 of the epidermal growth factor receptor gene in Chinese patients with lung adenocarcinoma
por: Zhao, Qingchun, et al.
Publicado: (2015)

Structure–immunomodulatory activity relationships of dietary polysaccharides
por: Chen, Ruoxin, et al.
Publicado: (2022)

Thyroid nodules in centenarians: prevalence and relationship to lifestyle characteristics and dietary habits
por: Yao, Yao, et al.
Publicado: (2018)

Relationship between brain metastasis and thyroid transcription factor 1
por: Kut, Engin, et al.
Publicado: (2023)

Thyroid cancer 1 (C8orf4) shows high expression, no mutation and reduced methylation level in lung cancers, and its expression correlates with β-catenin and DNMT1 expression and poor prognosis
por: Zheng, Yi-Wen, et al.
Publicado: (2017)

Transcription start site‐level expression of thyroid transcription factor 1 isoforms in lung adenocarcinoma and its clinicopathological significance
por: Sano, Kei, et al.
Publicado: (2021)

Metabolic syndrome and its components are associated with thyroid volume in adolescents
por: Xiao, Yang, et al.
Publicado: (2021)

Down-Regulation of Activating Transcription Factor 3 (ATF3) in Hepatoblastoma and Its Relationship with Ferroptosis
por: Li, Jing-Xiao, et al.
Publicado: (2021)

Osteopontin expression in papillary thyroid carcinoma and its relationship with the BRAF mutation and tumor characteristics
por: Kang, Kyung Ho
Publicado: (2013)

Resveratrol antagonizes thyroid hormone-induced expression of checkpoint and proliferative genes in oral cancer cells
por: Lin, Chia-Cheng, et al.
Publicado: (2019)

MOF Regulates TNK2 Transcription Expression to Promote Cell Proliferation in Thyroid Cancer
por: Li, Danyang, et al.
Publicado: (2020)

A High-Throughput Screening System for Populus Wood-Associated Transcription Factors and Its Application to Lignin Regulation
por: Zhuang, Yamei, et al.
Publicado: (2022)

Study of Structure and Permeability Relationship of Flavonoids in Caco-2 Cells
por: Fang, Yajing, et al.
Publicado: (2017)

Targeting the Sonic Hedgehog Pathway to Suppress the Expression of the Cancer Stem Cell (CSC)—Related Transcription Factors and CSC-Driven Thyroid Tumor Growth
por: Lu, Yurong, et al.
Publicado: (2021)

Immune profiling identifies CD8(+) T-cell subset signatures as prognostic markers for recurrence in papillary thyroid cancer
por: Chen, Zhen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sbjmktenp0mnt53fupp0vsuket