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Genetic variation at ERBB3/IKZF4 and sexual dimorphism in epitope spreading in single autoantibody-positive relatives

AIMS/HYPOTHESIS: We examined whether the non-HLA susceptibility locus ERBB3/IKZF4 influences progression of type 1 diabetes stage specifically according to sex. METHODS: SNPs of ERBB3 (rs2292239 T/G) and IKZF4 (rs1701704 G/T) were screened by allelic discrimination quantitative PCR assay in first-de...

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Detalles Bibliográficos
Autores principales:	Vandewalle, Julie, Van der Auwera, Bart J., Amin, Henna, Quartier, Erik, Desouter, Aster K., Tenoutasse, Sylvie, Gillard, Pieter, De Block, Christophe, Keymeulen, Bart, Gorus, Frans K., Van de Casteele, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494691/ https://www.ncbi.nlm.nih.gov/pubmed/34448034 http://dx.doi.org/10.1007/s00125-021-05546-9

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